Characterization of Human Duodenal Fluids in Fasted and Fed State Conditions
نویسندگان
چکیده
منابع مشابه
Biomimetic PVPA in vitro model for estimation of the intestinal drug permeability using fasted and fed state simulated intestinal fluids.
A prerequisite for successful oral drug therapy is the drug's ability to cross the gastrointestinal barrier. Considering the increasing number of new chemical entities in modern drug discovery, reliable and fast in vitro models are required for early and efficient prediction of intestinal permeability. To mimic the intestinal environment, use of biorelevant media may provide valuable informatio...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Sciences
سال: 2016
ISSN: 0022-3549
DOI: 10.1002/jps.24603